WIN 55,212-2 mesylate

Research use only, not for human use.

WIN 55,212-2 mesylate (WIN 55212-2) is a potent cannabinoid receptor agonist with Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively.

WIN 55,212-2 mesylate (WIN 55212-2) is a potent cannabinoid receptor agonist with Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively; increases extracellular glutamate levels, displaying a bell-shaped concentration-response curve at 0.01-100 nM; increases dialysate glutamate levels the prefrontal cortex from of the awake rats, also demonstrates anticonvulsant effect in vivo pre-treated with 20 mg/kg of pioglitazone.

R)-(+)-WIN 55212;WIN 55212-2

GPCR/G Protein

Cannabinoid Receptor

CB1R;CB2R

Neurological Disease

——

131543-23-2

522.62

C28H30N2O6S

>98% (HPLC)

DMSO: ≥ 34 mg/mL

O=C(C1=C(C)N2[C@H](CN3CCOCC3)COC4=CC=CC1=C24)C5=C6C=CC=CC6=CC=C5.CS(=O)(O)=O

Methanone, [(3R)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-, methanesulfonate (1:1)

(-20℃)

With Ice Pack

≥ 2 years